DBM-GGFG-NH-O-CO-Exatecan

Catalog No.: A41423
Drug-Linker Conjugate for ADC
DBM-GGFG-NH-O-CO-Exatecan is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications, functioning primarily as a topoisomerase I inhibitor. It is utilized in the synthesis of ADC molecules to effectively target and deliver cytotoxic agents to specific cell populations, enhancing therapeutic efficacy while minimizing systemic toxicity. This compound plays a vital role in cancer research by facilitating the development of targeted therapies.
Grouped product items
Size Price Stock Qty
5mg
$635.00
In stock
10mg
$1,040.00
In stock
25mg
$2,100.00
In stock
50mg
$3,280.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDBM-GGFG-NH-O-CO-Exatecan is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications, functioning primarily as a topoisomerase I inhibitor. It is utilized in the synthesis of ADC molecules to effectively target and deliver cytotoxic agents to specific cell populations, enhancing therapeutic efficacy while minimizing systemic toxicity. This compound plays a vital role in cancer research by facilitating the development of targeted therapies.
Product Information
Catalog NumA41423
FormulaC52H54Br2FN9O13
Molecular Weight1191.84
CAS Number2769152-95-4
SMILESO=C(C(Br)=C(C1=O)Br)N1CCCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCOCC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O)=O
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