Defactinib analogue-1

Catalog No.: A34265
Fak Ligand
Defactinib analogue-1 is a ligand that targets focal adhesion kinase (FAK), facilitating the development of proteolysis-targeting chimeras (PROTACs) like FAK degrader 1. This compound is essential for research applications focused on FAK modulation and its role in cellular signaling pathways related to cancer progression and metastasis. Its utility in synthesizing targeted protein degraders makes it a valuable tool for investigating FAK-associated biological processes.
Grouped product items
Size Price Stock Qty
5mg
$330.00
In stock
10mg
$565.00
In stock
25mg
$1,180.00
In stock
50mg
$1,845.00
In stock
100mg
$2,880.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDefactinib analogue-1 is a ligand that targets focal adhesion kinase (FAK), facilitating the development of proteolysis-targeting chimeras (PROTACs) like FAK degrader 1. This compound is essential for research applications focused on FAK modulation and its role in cellular signaling pathways related to cancer progression and metastasis. Its utility in synthesizing targeted protein degraders makes it a valuable tool for investigating FAK-associated biological processes.
Product Information
Catalog NumA34265
FormulaC20H20F3N5O3S
Molecular Weight467.47
CAS Number2296719-34-9
SMILESCS(=O)(N(C)C1=CC=CC(CNC2=NC(NC3=CC=C(O)C=C3)=NC=C2C(F)(F)F)=C1)=O
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