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Deruxtecan is an ADC drug-linker conjugate composed of a derivative of DX-8951 (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 9.67 mL | 48.35 mL | 96.71 mL |
| 0.5 mM | 1.93 mL | 9.67 mL | 19.34 mL |
| 1 mM | 0.97 mL | 4.84 mL | 9.67 mL |
| 5 mM | 0.19 mL | 0.97 mL | 1.93 mL |
*The above data is based on the productmolecular weight 1034.05. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21522 |
|---|---|
| CAS No. | 1599440-13-7 |
| Formula | C52H56FN9O13 |
| M. Wt | 1034.05 |
| Purity | >98% |
| SMILES | O=C(C=CC1=O)N1CCCCCC(NCC(NCC(N[[email protected]@H](CC2=CC=CC=C2)C(NCC(NCOCC(N[[email protected]@H]3C4=C5C(C(N6C5)=CC([[email protected]](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C48)=O)=O)=O)=O)=O)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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