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DMBA-SIL-Mal-MMAE

Catalog No.: A41575
Drug-linker Conjugate for ADC
DMBA-SIL-Mal-MMAE is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications, featuring the potent antitumor cytotoxin monomethyl auristatin E (MMAE), a tubulin inhibitor. This compound provides targeted delivery of MMAE to cancer cells via a stable linkage with DMBA-SIL-Mal, enhancing its therapeutic efficacy. It serves as a valuable tool for researchers investigating ADCs in cancer therapy and drug development.
DMBA-SIL-Mal-MMAE 2923885-49-6 Drug-linker Conjugate for ADC
Grouped product items
Size Price Stock Qty
5mg
$740.00
In stock
10mg
$1,220.00
In stock
25mg
$2,520.00
In stock
50mg
$3,935.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDMBA-SIL-Mal-MMAE is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications, featuring the potent antitumor cytotoxin monomethyl auristatin E (MMAE), a tubulin inhibitor. This compound provides targeted delivery of MMAE to cancer cells via a stable linkage with DMBA-SIL-Mal, enhancing its therapeutic efficacy. It serves as a valuable tool for researchers investigating ADCs in cancer therapy and drug development.
Product Information
Catalog NumA41575
FormulaC72H106N8O20
Molecular Weight1403.65
CAS Number2923885-49-6
SMILESO[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OC(C3=CC=C(C=C3)NC(OCC4=CC(OC)=CC(OC)=C4)=O)C(NCCOCCOCCOCCOCCN5C(C=CC5=O)=O)=O)=O)=O)=O)=O)OC)=O
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC