Duocarmycin

Catalog No.: A18472

Duocarmycin

Duocarmycin Chemical Structure

CAS NO. 1116745-06-2

Duocarmycin is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity. Duocarmycin is a DNA minor groove binding alkylating agent and explored as drug?Cantibody conjugates (ADCs) .

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5 mg
$350.00
10 mg
$650.00
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Biological Activity

Duocarmycin is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity. Duocarmycin is a DNA minor groove binding alkylating agent and explored as drug?Cantibody conjugates (ADCs) .
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.55 mL 107.77 mL 215.54 mL
0.5 mM 4.31 mL 21.55 mL 43.11 mL
1 mM 2.16 mL 10.78 mL 21.55 mL
5 mM 0.43 mL 2.16 mL 4.31 mL

*The above data is based on the productmolecular weight 463.96. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18472
M. Wt 463.96
Formula C26H26ClN3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1116745-06-2
SMILES O=C(N1C[[email protected]@H](CCl)C2=C1C=C(O)C3=CC=CC=C23)C(N4)=CC5=C4C=CC(OCCN(C)C)=C5

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