E-3810

Catalog No.: A15073

VEGFR/FGFR Inhibitor

E-3810 Chemical Structure

CAS NO. 1058137-23-7

E-3810 is a potent and selective dual inhibitor of VEGF and FGF receptors with IC50 values of 7 nM, 25 nM, 10 nM, 17.5 nM and 82.5 nM for VEGFR-1, VEGFR-2, VEGFR-3, FGFR-1 and FGFR-2, respectively.

Availability: In stock

Package Price Qty
5 mg
$190.00
10 mg
$310.00
50 mg
$780.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

E-3810 is a potent and selective dual inhibitor of VEGF and FGF receptors with IC50 values of 7 nM, 25 nM, 10 nM, 17.5 nM and 82.5 nM for VEGFR-1, VEGFR-2, VEGFR-3, FGFR-1 and FGFR-2, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.55 mL 112.74 mL 225.48 mL
0.5 mM 4.51 mL 22.55 mL 45.1 mL
1 mM 2.25 mL 11.27 mL 22.55 mL
5 mM 0.45 mL 2.25 mL 4.51 mL

*The above data is based on the productmolecular weight 443.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15073
Actions Inhibitor
M. Wt 443.49
Formula C26H25N3O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1058137-23-7
Synonyms E 3810, E3810, Lucitanib
SMILES CNC(=O)C1=CC=CC2=C1C=CC(=C2)OC3=C4C=C(C(=CC4=NC=C3)OCC5(CC5)N)OC

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