E7080 (Lenvatinib)

Name: E7080 (Lenvatinib)
SKU: A10340
Price: 50 USD
Rating: 5 (8 reviews)

Catalog No.: A10340

VEGFR Inhibitor

Adooq's E7080 (Lenvatinib) has been cited by 8 publications

E7080 is a multi-kinase inhibitor that inhibits both VEGFR2 and VEGFR3 kinases.

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Important Notice: For research use only. We do not sell to patients.

Data Sheet

SDS

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Adooq Products cited in reputable paper

Adooq's E7080 (Lenvatinib) has been cited by 8 publications

Mai Nakahara, .et al. , Biomed Rep, 2022, Aug 3;17(4):78 PMID: 36158319

Paula Sagmeister, .et al. , J Hepatocell Carcinoma, 2022, Jul 9;9:595-607 PMID: 35845819

Aya Hasan Alshammari, .et al. , Biochem Pharmacol, 2022, Mar;197:114914 PMID: 35041812

Keisuke Enomoto, .et al. , Cancers (Basel), 2021, Feb 18;13(4):862 PMID: 33670725

Jindal A, .et al. , J Transl Sci, 2020, 7: 1-10

Koide H, .et al. , Xenobiotica, 2018, Oct;48(10):1059-1071 PMID: 29034773

Fujita KI, .et al. , J Pharm Sci, 2017, Sep;106(9):2632-2641 PMID: 28479358

Tomoko Ogawa-Morita, .et al. , Int J Anal Chem, 2017, 2017: 2341876 PMID: 28680445

Biological Activity

Discription

E7080 is a multi-kinase inhibitor that inhibits both VEGFR2 and VEGFR3 kinases.

Targets

Target	Value

Chemical Information

Catalog Num	A10340
Formula	C21H19ClN4O4
Molecular Weight	426.9
CAS Number	417716-92-8
SMILES	COC1=CC2=NC=CC(=C2C=C1C(=O)N)OC3=CC(=C(C=C3)NC(=O)NC4CC4)Cl
Synonyms	E-7080
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	Warmed: 35 mg/mL (81.99 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% methylcellulose	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.42 mL	117.12 mL	234.25 mL
0.5 mM	4.68 mL	23.42 mL	46.85 mL
1 mM	2.34 mL	11.71 mL	23.42 mL
5 mM	0.47 mL	2.34 mL	4.68 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Product Name	Price	Stock
E7080 5mg	$50.00	In stock
E7080 10mg	$70.00	In stock
E7080 50mg	$150.00	In stock
E7080 100mg	$200.00	In stock
*E7080 (Lenvatinib) 10mM 1mL in DMSO**	$50.00	In stock