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E7080 (Lenvatinib)

Catalog No.: A10340
VEGFR Inhibitor
Adooq's E7080 (Lenvatinib) has been cited by 9 publications
E7080 is a multi-kinase inhibitor that inhibits both VEGFR2 and VEGFR3 kinases.
E7080 (Lenvatinib)
Grouped product items
Size Price Stock Qty
5mg
$35.00
In stock
10mg
$50.00
In stock
25mg
$80.00
In stock
50mg
$115.00
In stock
100mg
$180.00
In stock
500mg
$455.00
In stock
10mM * 1mL in DMSO
$50.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's E7080 (Lenvatinib) has been cited by 9 publications
  • Majid Momeny, .et al. , EMBO Mol Med, 2024, Jun 17 PMID: 38886591
  • Mai Nakahara, .et al. , Biomed Rep, 2022, Aug 3;17(4):78 PMID: 36158319
  • Paula Sagmeister, .et al. , J Hepatocell Carcinoma, 2022, Jul 9;9:595-607 PMID: 35845819
  • Aya Hasan Alshammari, .et al. , Biochem Pharmacol, 2022, Mar;197:114914 PMID: 35041812
  • Keisuke Enomoto, .et al. , Cancers (Basel), 2021, Feb 18;13(4):862 PMID: 33670725
  • Jindal A, .et al. , J Transl Sci, 2020, 7: 1-10
  • Koide H, .et al. , Xenobiotica, 2018, Oct;48(10):1059-1071 PMID: 29034773
  • Fujita KI, .et al. , J Pharm Sci, 2017, Sep;106(9):2632-2641 PMID: 28479358
  • Tomoko Ogawa-Morita, .et al. , Int J Anal Chem, 2017, 2017: 2341876 PMID: 28680445
    • Biological Activity
    Discription E7080 is a multi-kinase inhibitor that inhibits both VEGFR2 and VEGFR3 kinases.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A10340
    Formula C21H19ClN4O4
    Molecular Weight 426.9
    CAS Number 417716-92-8
    SMILES COC1=CC2=NC=CC(=C2C=C1C(=O)N)OC3=CC(=C(C=C3)NC(=O)NC4CC4)Cl
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Solubility
    In vitro (25°C) DMSO Warmed: 35 mg/mL (81.99 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 0.5% methylcellulose 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 23.42 mL 117.12 mL 234.25 mL
    0.5 mM 4.68 mL 23.42 mL 46.85 mL
    1 mM 2.34 mL 11.71 mL 23.42 mL
    5 mM 0.47 mL 2.34 mL 4.68 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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    Protein Tyrosine Kinases > VEGFR
    Angiogenesis > VEGFR
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