Echinomycin

Catalog No.: A14021

HIF-1α inhibitor

Echinomycin

Echinomycin Chemical Structure

CAS NO. 512-64-1

Hypoxia-inducible factor-1 (HIF-1) is a transcription factor that controls genes involved in glycolysis, angiogenesis, migration, and invasion. Echinomycin is a cell-permeable inhibitor of HIF-1-mediated gene transcription

Availability: In stock

Package Price Qty
5 mg

Regular Price: $220.00

Special Price $176.00

10 mg

Regular Price: $400.00

Special Price $320.00

25 mg

Regular Price: $900.00

Special Price $720.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

Hypoxia-inducible factor-1 (HIF-1) is a transcription factor that controls genes involved in glycolysis, angiogenesis, migration, and invasion. Echinomycin is a cell-permeable inhibitor of HIF-1-mediated gene transcription
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 9.08 mL 45.4 mL 90.8 mL
0.5 mM 1.82 mL 9.08 mL 18.16 mL
1 mM 0.91 mL 4.54 mL 9.08 mL
5 mM 0.18 mL 0.91 mL 1.82 mL

*The above data is based on the productmolecular weight 1101.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A14021
Actions Inhibitor
M. Wt 1101.3
Formula C51H64N12O12S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 512-64-1
Synonyms Antibiotic A 654I, NSC 526417, Quinomycin A, SK 302B, NSC 13502
SMILES CC1C(=O)N(C2CSC(C(C(=O)N(C(C(=O)OC[[email protected]](C(=O)N1)NC(=O)C3=NC4=CC=CC=C4N=C3)C(C)C)C)N(C(=O)C(NC(=O)[[email protected]@H](COC(=O)C(N(C2=O)C)C(C)C)NC(=O)C5=NC6=CC=CC=C6N=C5)C)C)SC)C

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