Ecromeximab, also known as KM 871 and KW 2871, is a chimeric monoclonal antibody of the IgG-κ isotype derived from mouse. It specifically targets ganglioside GD3, a sialic acid-containing glycosphingolipid overexpressed in various tumor cells. This antibody is produced in YB2/0 rat hybridoma cells, ensuring a high level of purity and specificity. Ecromeximab is utilized primarily in research focused on the therapeutic targeting of cancers that express ganglioside GD3.
Ecromeximab, also known as KM 871 and KW 2871, is a chimeric monoclonal antibody of the IgG-κ isotype derived from mouse. It specifically targets ganglioside GD3, a sialic acid-containing glycosphingolipid overexpressed in various tumor cells. This antibody is produced in YB2/0 rat hybridoma cells, ensuring a high level of purity and specificity. Ecromeximab is utilized primarily in research focused on the therapeutic targeting of cancers that express ganglioside GD3.
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Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
Frequently Asked Questions
What are Biosimilar Antibodies?
Biosimilar antibodies are research-grade recombinant antibodies designed to closely resemble approved therapeutic antibodies in terms of amino acid sequence, structural characteristics, and biological activity. These antibodies are generated using recombinant expression technologies and retain the same variable regions as their corresponding reference therapeutics, thereby preserving target specificity and binding affinity. Owing to these properties, biosimilar antibodies serve as reliable and cost-effective research reagents for applications in drug discovery, pharmacological studies, and basic biomedical research.
Research-grade biosimilar antibodies have been successfully expressed and functionally validated against a wide range of widely studied targets. These antibodies can be directly utilized as positive control reagents in drug discovery programs, as well as reference tools for rapid verification of the biological functions of target proteins in biochemical and cellular assays.
