ER-27319 is a potent and selective Spleen Tyrosine Kinase (SYK) inhibitor, known for its ability to suppress the tyrosine phosphorylation of SYK and thereby inhibit its enzymatic activity. This compound effectively blocks the release of antigen-induced allergic mediators from human and rat mast cells, exhibiting an IC50 of 10 μM. ER-27319 is a valuable tool for research in the field of allergic diseases, particularly in studies focused on mast cell activation and modulation.
ER-27319 is a potent and selective Spleen Tyrosine Kinase (SYK) inhibitor, known for its ability to suppress the tyrosine phosphorylation of SYK and thereby inhibit its enzymatic activity. This compound effectively blocks the release of antigen-induced allergic mediators from human and rat mast cells, exhibiting an IC50 of 10 μM. ER-27319 is a valuable tool for research in the field of allergic diseases, particularly in studies focused on mast cell activation and modulation.
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