FAK-IN-29 is a potent selective inhibitor of focal adhesion kinase (FAK), exhibiting an IC50 of 0.5 nM. This compound demonstrates significant antitumor activity by inhibiting proliferation and colony formation of MDA-MB-231 cells, as well as inducing cell cycle arrest and apoptosis. FAK-IN-29 is a valuable tool for investigating the role of FAK in various tumors, particularly in the research of triple-negative breast cancer.
FAK-IN-29 is a potent selective inhibitor of focal adhesion kinase (FAK), exhibiting an IC50 of 0.5 nM. This compound demonstrates significant antitumor activity by inhibiting proliferation and colony formation of MDA-MB-231 cells, as well as inducing cell cycle arrest and apoptosis. FAK-IN-29 is a valuable tool for investigating the role of FAK in various tumors, particularly in the research of triple-negative breast cancer.
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