FG-2216

Catalog No.: A15530

HIF-prolyl hydroxylase inhibitor

FG-2216

FG-2216 Chemical Structure

CAS NO. 223387-75-5

FG-2216 is a potent HIF-prolyl hydroxylase inhibitor with IC50 of 3.9 uM for PDH2 enzyme; orally bioavailable and induced significant and reversible Epo induction in vivo,

Availability: In stock

Package Price Qty
5 mg

Regular Price: $120.00

Special Price $108.00

10 mg

Regular Price: $190.00

Special Price $171.00

25 mg

Regular Price: $420.00

Special Price $378.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

FG-2216 is a potent HIF-prolyl hydroxylase inhibitor with IC50 of 3.9 uM for PDH2 enzyme; orally bioavailable and induced significant and reversible Epo induction in vivo,
Targets
PHD2
3.9 μM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.63 mL 178.15 mL 356.3 mL
0.5 mM 7.13 mL 35.63 mL 71.26 mL
1 mM 3.56 mL 17.82 mL 35.63 mL
5 mM 0.71 mL 3.56 mL 7.13 mL

*The above data is based on the productmolecular weight 280.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A15530
Actions Inhibitor
M. Wt 280.66
Formula C12H9ClN2O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 223387-75-5
Synonyms YM-311
SMILES C1=CC=C2C(=C1)C(=C(N=C2Cl)C(=O)NCC(=O)O)O

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