FGF 2 Human, Thermostable

FGF-Basic Thermostable is a stabilized form of FGF-2 growth factor which enables a novel method to produce FGF2-dependent cell cultures more efficiently, having less media changes. FGF-Basic Thermostable can maintain its biological activity even after five days at 37°C. The increase in the stability of FGF2 in cell-culture enables a more homogenous, undifferentiated stem cell culture, while saving scientists crucial time and money, as frequent supplementation of FGF-basic and the everyday medium change is not necessary. Thermostable FGF-2 is a hyperstable protein. The Thermal stability of the protein is increased by 15°C compared to the wild-type FGF-2. Thermostable FGF-2 is more than 5-times prolonged half-life in human cell culture incubated at 37°C. The FGF-2 Thermostable protein is engineered with fully retained biological function and has no harmful stabilizing additives.Thermostable FGF2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 175 amino acids including a 20 aa His tag and thrombin cleavage recognition site at N-terminus. The total calculated molecular mass is 19.4kDa.