FGFR1/DDR2 inhibitor 1

Catalog No.: A18716

FGFR1/DDR2 inhibitor

FGFR1/DDR2 inhibitor 1

FGFR1/DDR2 inhibitor 1 Chemical Structure

CAS NO. 2308497-58-5

FGFR1/DDR2 inhibitor 1 is an inhibitor of fibroblast growth factor receptor 1 (FGFR1) and discoindin domain receptor 2 (DDR2), with IC50 values of 31.1 nM, 108.4 nM and 3.2 nM for FGFR1, KG-1, and DDR2, respectively.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $350.00

Special Price $280.00

10 mg

Regular Price: $650.00

Special Price $520.00

50 mg

Regular Price: $2,000.00

Special Price $1,600.00

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Biological Activity

FGFR1/DDR2 inhibitor 1 is an inhibitor of fibroblast growth factor receptor 1 (FGFR1) and discoindin domain receptor 2 (DDR2), with IC50 values of 31.1 nM, 108.4 nM and 3.2 nM for FGFR1, KG-1, and DDR2, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.94 mL 99.7 mL 199.4 mL
0.5 mM 3.99 mL 19.94 mL 39.88 mL
1 mM 1.99 mL 9.97 mL 19.94 mL
5 mM 0.4 mL 1.99 mL 3.99 mL

*The above data is based on the productmolecular weight 501.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18716
Actions Inhibitor
CAS No. 2308497-58-5
Formula C28H22F3N5O
M. Wt 501.5
Purity >98%
SMILES O=C(NC1=CC=CC(C(F)(F)F)=C1)C2=CC=C(C)C(C3=CC4=C(C=C3)C(C5=CN(C6CC6)N=C5)=NN4)=C2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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