FLT3-IN-15 is a potent and orally bioavailable inhibitor of the FLT3 receptor, exhibiting IC50 values of 0.87 nM for FLT3 and 0.32 nM for the FLT3/D835Y mutant. This compound is primarily utilized in research related to acute myeloid leukemia, providing insights into the therapeutic potential of targeting aberrant FLT3 signaling pathways in cancer treatment.
FLT3-IN-15 is a potent and orally bioavailable inhibitor of the FLT3 receptor, exhibiting IC50 values of 0.87 nM for FLT3 and 0.32 nM for the FLT3/D835Y mutant. This compound is primarily utilized in research related to acute myeloid leukemia, providing insights into the therapeutic potential of targeting aberrant FLT3 signaling pathways in cancer treatment.
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