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Biological Activity
Flumatinib is a multi-kinase inhibitor with IC50 Values of 1.2 nM, 307.6 nM and 2662 nM for c-Abl, PDGFRbeta and c-Kit respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.77 mL | 88.87 mL | 177.75 mL |
| 0.5 mM | 3.55 mL | 17.77 mL | 35.55 mL |
| 1 mM | 1.78 mL | 8.89 mL | 17.77 mL |
| 5 mM | 0.36 mL | 1.78 mL | 3.55 mL |
*The above data is based on the productmolecular weight 562.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16258 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 895519-90-1 |
| Formula | C29H29F3N8O |
| M. Wt | 562.59 |
| Purity | >98% |
| Synonyms | HHGV678, HHGV 678 , HHGV-678 |
| SMILES | CC1=C(NC2=NC=CC(C3=CN=CC=C3)=N2)C=C(NC(C4=CC(C(F)(F)F)=C(CN5CCN(C)CC5)C=C4)=O)C=N1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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