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Fmoc-Gly-Gly-Phe-Gly-Paclitaxel

Catalog No.: A41574
Drug-Linker Conjugates for ADC
Fmoc-Gly-Gly-Phe-Gly-Paclitaxel is a drug-linker conjugate designed for use in antibody-drug conjugate (ADC) applications. This compound combines the Fmoc-Gly-Gly-Phe-OH linker with the potent tubulin polymerization inhibitor, Paclitaxel, facilitating targeted delivery in cancer research. Its unique structure enables the selective treatment of tumor cells, making it a valuable tool for studying ADC efficacy and mechanisms in oncology.
Fmoc-Gly-Gly-Phe-Gly-Paclitaxel 3061439-05-9 Drug-Linker Conjugates for ADC
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionFmoc-Gly-Gly-Phe-Gly-Paclitaxel is a drug-linker conjugate designed for use in antibody-drug conjugate (ADC) applications. This compound combines the Fmoc-Gly-Gly-Phe-OH linker with the potent tubulin polymerization inhibitor, Paclitaxel, facilitating targeted delivery in cancer research. Its unique structure enables the selective treatment of tumor cells, making it a valuable tool for studying ADC efficacy and mechanisms in oncology.
Product Information
Catalog NumA41574
FormulaC78H82N6O20
Molecular Weight1423.51
CAS Number3061439-05-9
SMILESCC(O[C@]12[C@@]3([H])[C@@H]([C@]4(C(C)(C([C@H](C([C@@]3([C@H](C[C@@]1([H])OC2)O)C)=O)OC(C)=O)=C([C@H](C4)OC([C@H](OCNC(CNC([C@@H](NC(CNC(CNC(OCC5C6=CC=CC=C6C7=CC=CC=C75)=O)=O)=O)CC8=CC=CC=C8)=O)=O)[C@H](C9=CC=CC=C9)NC(C%10=CC=CC=C%10)=O)=O)C)C)O)OC(C%11=CC=CC=C%11)=O)=O
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC