Foretinib (GSK1363089, XL880)
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | Foretinib (GSK1363089), a multikinase inhibitor of c-Met and VEGFR-2, blocks proliferation, induces Anoikis, and impairs ovarian cancer metastasis. | ||
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Targets |
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Catalog Num | A10998 |
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Formula | C34H34F2N4O6 |
Molecular Weight | 632.7 |
CAS Number | 849217-64-7 |
SMILES | COC1=CC2=C(C=CN=C2C=C1OCCCN3CCOCC3)OC4=C(C=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F |
Synonyms | GSK089, EXEL-2880 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 87 mg/mL (137.51 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 15.81 mL | 79.03 mL | 158.05 mL |
0.5 mM | 3.16 mL | 15.81 mL | 31.61 mL |
1 mM | 1.58 mL | 7.9 mL | 15.81 mL |
5 mM | 0.32 mL | 1.58 mL | 3.16 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2