Foretinib (GSK1363089, XL880)

Foretinib (GSK1363089), a multikinase inhibitor of c-Met and VEGFR-2, blocks proliferation, induces Anoikis, and impairs ovarian cancer metastasis.
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Size Price Stock Qty
2mg
$25.00
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5mg
$35.00
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10mg
$65.00
In stock
25mg
$115.00
In stock
50mg
$210.00
In stock
100mg
$355.00
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500mg
$885.00
In stock
10mM * 1mL in DMSO
$65.00
In stock
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Important Notice: For research use only. We do not sell to patients.

Adooq Products cited in reputable paper
Adooq's Foretinib (GSK1363089, XL880) has been cited by 6 publications
  • Ayaka Kojima, .et al. , Xenobiotica, 2022, Jul;52(7):669-675 PMID: 36251932
  • Narges K Gortany, .et al. , Cancer Chemother Pharmacol, 2021, Mar 10 PMID: 33688998
  • Hamzehlou S, .et al. , Eur J Pharmacol, 2019, Nov 15;863:172705 PMID: 31574259
  • Hayato Ogura, .et al. , Sci Rep, 2017, 7: 5519 PMID: 28717217
  • Fuse MJ, .et al. , Mol Cancer Ther, 2017, Oct;16(10):2130-2143 PMID: 28751539
  • Ryohei Katayama, .et al. , Clin Cancer Res, 2015, Jan 1; 21(1): 166-174 PMID: 25351743
  • Biological Activity
    Discription Foretinib (GSK1363089), a multikinase inhibitor of c-Met and VEGFR-2, blocks proliferation, induces Anoikis, and impairs ovarian cancer metastasis.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A10998
    Formula C34H34F2N4O6
    Molecular Weight 632.7
    CAS Number 849217-64-7
    SMILES COC1=CC2=C(C=CN=C2C=C1OCCCN3CCOCC3)OC4=C(C=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F
    Synonyms GSK089, EXEL-2880
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 87 mg/mL (137.51 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 15.81 mL 79.03 mL 158.05 mL
    0.5 mM 3.16 mL 15.81 mL 31.61 mL
    1 mM 1.58 mL 7.9 mL 15.81 mL
    5 mM 0.32 mL 1.58 mL 3.16 mL
    Useful Calculator

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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