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Biological Activity
Fruquintinib is an orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-angiogenic and antineoplastic activities.
| In vitro | DMSO | 6 mg/mL (15.25 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.42 mL | 127.1 mL | 254.2 mL |
| 0.5 mM | 5.08 mL | 25.42 mL | 50.84 mL |
| 1 mM | 2.54 mL | 12.71 mL | 25.42 mL |
| 5 mM | 0.51 mL | 2.54 mL | 5.08 mL |
*The above data is based on the productmolecular weight 393.3927. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A14393 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1194506-26-7 |
| Formula | C21H19N3O5 |
| M. Wt | 393.3927 |
| Purity | >98% |
| Synonyms | HMPL-013, HMPL 013, HMPL013 |
| SMILES | O=C(C1=C(C)OC2=CC(OC3=C4C=C(OC)C(OC)=CC4=NC=N3)=CC=C12)NC |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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