Fruquintinib

Catalog No.: A14393

VEGFR inhibitor

Fruquintinib

Fruquintinib Chemical Structure

CAS NO. 1194506-26-7

Fruquintinib is an orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-angiogenic and antineoplastic activities.

Availability: In stock

Package Price Qty
5 mg
$50.00
10 mg
$85.00
25 mg
$150.00
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Biological Activity

Fruquintinib is an orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-angiogenic and antineoplastic activities.
In vitro DMSO 6 mg/mL (15.25 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.42 mL 127.1 mL 254.2 mL
0.5 mM 5.08 mL 25.42 mL 50.84 mL
1 mM 2.54 mL 12.71 mL 25.42 mL
5 mM 0.51 mL 2.54 mL 5.08 mL

*The above data is based on the productmolecular weight 393.3927. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14393
Actions Inhibitor
CAS No. 1194506-26-7
Formula C21H19N3O5
M. Wt 393.3927
Solubility DMSO
Purity >98%
Synonyms HMPL-013, HMPL 013, HMPL013
SMILES O=C(C1=C(C)OC2=CC(OC3=C4C=C(OC)C(OC)=CC4=NC=N3)=CC=C12)NC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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