GDC-0152

Catalog No.: A14135
IAP antagonist
GDC-0152 is a second mitochondrial activator of caspases (Smac) mimetic inhibitor of IAPs (Inhibitor of Apoptosis Proteins) with potential antineoplastic activity.
Grouped product items
Product Name Price Stock Qty
GDC-0152 10mg
$135.00
In stock
GDC-0152 25mg
$270.00
In stock
GDC-0152 50mg
$405.00
In stock
GDC-0152 10mM * 1mL in DMSO
$135.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription GDC-0152 is a second mitochondrial activator of caspases (Smac) mimetic inhibitor of IAPs (Inhibitor of Apoptosis Proteins) with potential antineoplastic activity.
Targets
Target Value
Product Information
Catalog Num A14135
Formula C25H34N6O3S
Molecular Weight 498.64
CAS Number 873652-48-3
SMILES CC(C(=O)NC(C1CCCCC1)C(=O)N2CCCC2C(=O)NC3=C(N=NS3)C4=CC=CC=C4)NC
Synonyms GDC0152, GDC 0152
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 98 mg/mL (196.53 mM)
Water 3 mg/mL (6.01 mM)
Ethanol 98 mg/mL (196.53 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.05 mL 100.27 mL 200.55 mL
0.5 mM 4.01 mL 20.05 mL 40.11 mL
1 mM 2.01 mL 10.03 mL 20.05 mL
5 mM 0.4 mL 2.01 mL 4.01 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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