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GDP-Fuc-AM-VcPAB-MMAE

Catalog No.: A41502
Drug-Linker Conjugates for ADC
GDP-Fuc-AM-VcPAB-MMAE is a conjugate of the cytotoxic agent Monomethyl auristatin E (MMAE) linked via a specific linker system. This precursor molecule plays a critical role in the development of antibody-drug conjugates (ADCs), facilitating targeted delivery of therapeutics in cancer research. Its utilization in experimental studies aids in the exploration of ADC efficacy and potential treatment pathways for neoplastic diseases.
GDP-Fuc-AM-VcPAB-MMAE 2762518-87-4 Drug-Linker Conjugates for ADC
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGDP-Fuc-AM-VcPAB-MMAE is a conjugate of the cytotoxic agent Monomethyl auristatin E (MMAE) linked via a specific linker system. This precursor molecule plays a critical role in the development of antibody-drug conjugates (ADCs), facilitating targeted delivery of therapeutics in cancer research. Its utilization in experimental studies aids in the exploration of ADC efficacy and potential treatment pathways for neoplastic diseases.
Product Information
Catalog NumA41502
FormulaC79H124N16O29P2
Molecular Weight1823.87
CAS Number2762518-87-4
SMILESO[C@H]1[C@@H](O)[C@H](N2C3=C(C(N=C(N3)N)=O)N=C2)O[C@@H]1CCOP(OP(O[C@H]4O[C@H]([C@H]([C@H]([C@@H]4O)O)O)CNC(CCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC5=CC=C(C=C5)COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N(C)[C@@H]([C@@H](C)CC)[C@H](OC)CC(N6[C@](CCC6)([H])[C@H](OC)[C@@H](C)C(N[C@H](C)[C@H](C7=CC=CC=C7)O)=O)=O)=O)=O)=O)=O)=O)=O)=O)(O)=O)(O)=O
SynonymsGDP-FAmSucMMAE
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC