GGTI-2147 is a potent inhibitor of geranylgeranyl transferase I (GGTase I). It effectively blocks the geranyl-geranylation of the small GTPase Rap1A, leading to a reduction in Rac1 activity and mitigation of OGD/R-induced neuronal apoptosis. This compound is valuable for research into neurodevelopmental disorders, including autism, depression, and schizophrenia.
GGTI-2147 is a potent inhibitor of geranylgeranyl transferase I (GGTase I). It effectively blocks the geranyl-geranylation of the small GTPase Rap1A, leading to a reduction in Rac1 activity and mitigation of OGD/R-induced neuronal apoptosis. This compound is valuable for research into neurodevelopmental disorders, including autism, depression, and schizophrenia.
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