Gilteritinib (ASP2215)

Catalog No.: A14411

FLT3/Axl inhibitor

Gilteritinib (ASP2215)

Gilteritinib (ASP2215) Chemical Structure

CAS NO. 1254053-43-4

Gilteritinib is a potent FLT3/AXL inhibitor, which showed potent antileukemic activity against AML with either or both FLT3-ITD and FLT3-D835 mutations.

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5 mg

Regular Price: $100.00

Special Price $80.00

10 mg

Regular Price: $150.00

Special Price $120.00

25 mg

Regular Price: $250.00

Special Price $200.00

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Biological Activity

Gilteritinib is a potent FLT3/AXL inhibitor, which showed potent antileukemic activity against AML with either or both FLT3-ITD and FLT3-D835 mutations.
In vitro DMSO 90 mg/mL (162.83 mM)
Water Insoluble
Ethanol 77 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.09 mL 90.46 mL 180.93 mL
0.5 mM 3.62 mL 18.09 mL 36.19 mL
1 mM 1.81 mL 9.05 mL 18.09 mL
5 mM 0.36 mL 1.81 mL 3.62 mL

*The above data is based on the productmolecular weight 552.71. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14411
Actions Inhibitor
CAS No. 1254053-43-4
Formula C29H44N8O3
M. Wt 552.71
Purity >98%
Synonyms ASP2215, ASP-2215, ASP 2215
SMILES CCC1=NC(=C(N=C1NC2CCOCC2)NC3=CC(=C(C=C3)N4CCC(CC4)N5CCN(CC5)C)OC)C(=O)N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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