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Gly-Gly-Phe-Gly-NH-O-CO-Exatecan hydrochloride

Catalog No.: A41339
Drug-Linker Conjugates for ADC
Gly-Gly-Phe-Gly-NH-O-CO-Exatecan hydrochloride is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. The linker comprises Gly-Gly-Phe-Gly-NH-O-CO, which is attached to Exatecan, a potent inhibitor of DNA topoisomerase I. This compound exhibits significant potential in cancer research, facilitating targeted delivery and enhanced therapeutic efficacy in anticancer treatments.
Gly-Gly-Phe-Gly-NH-O-CO-Exatecan hydrochloride 3053688-78-8 Drug-Linker Conjugates for ADC
Grouped product items
Size Price Stock Qty
5mg
$410.00
In stock
10mg
$670.00
In stock
25mg
$1,210.00
In stock
50mg
$1,680.00
In stock
100mg
$2,320.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGly-Gly-Phe-Gly-NH-O-CO-Exatecan hydrochloride is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. The linker comprises Gly-Gly-Phe-Gly-NH-O-CO, which is attached to Exatecan, a potent inhibitor of DNA topoisomerase I. This compound exhibits significant potential in cancer research, facilitating targeted delivery and enhanced therapeutic efficacy in anticancer treatments.
Product Information
Catalog NumA41339
FormulaC42H46ClFN8O10
Molecular Weight877.31
CAS Number3053688-78-8
SMILESCC1=C(F)C=C2C3=C1CC[C@H](NC(COCNC(CNC([C@H](CC4=CC=CC=C4)NC(CNC(CN)=O)=O)=O)=O)=O)C3=C5C(C(N6C5)=CC([C@@](O)(CC)C(OC7)=O)=C7C6=O)=N2.Cl
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC