Catalog No.: A11439

Bcr-Abl inhibitor


GNF 2 Chemical Structure

CAS NO. 778270-11-4

GNF 2 is a Bcr-abl inhibitor that inhibits proliferation and induces apoptosis in Bcr-abl-expressing cells.

Availability: In stock

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10 mg
25 mg
50 mg
10mM * 1mL in DMSO
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Biological Activity

GNF 2 is a Bcr-abl inhibitor that inhibits proliferation and induces apoptosis in Bcr-abl-expressing cells.
Bcr-Abl (SUP-B15 cell line) Bcr-Abl (K562 cell line)
268 nM273 nM
In vitro DMSO 67 mg/mL (178.99 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.72 mL 133.58 mL 267.17 mL
0.5 mM 5.34 mL 26.72 mL 53.43 mL
1 mM 2.67 mL 13.36 mL 26.72 mL
5 mM 0.53 mL 2.67 mL 5.34 mL

*The above data is based on the productmolecular weight 374.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11439
Actions Inhibitor
CAS No. 778270-11-4
Formula C18H13F3N4O2
M. Wt 374.3
Purity >98%
Synonyms GNF2,GNF-2

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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