GNF 2

Catalog No.: A11439

Bcr-Abl inhibitor

GNF 2

GNF 2 Chemical Structure

CAS NO. 778270-11-4

GNF 2 is a Bcr-abl inhibitor that inhibits proliferation and induces apoptosis in Bcr-abl-expressing cells.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $120.00

Special Price $108.00

25 mg

Regular Price: $250.00

Special Price $225.00

50 mg

Regular Price: $450.00

Special Price $405.00

10mM * 1mL in DMSO

Regular Price: $104.00

Special Price $93.60

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

GNF 2 is a Bcr-abl inhibitor that inhibits proliferation and induces apoptosis in Bcr-abl-expressing cells.
Targets
Bcr-Abl (SUP-B15 cell line) Bcr-Abl (K562 cell line)
268 nM273 nM
In vitro DMSO 74 mg/mL (197.69 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.72 mL 133.58 mL 267.17 mL
0.5 mM 5.34 mL 26.72 mL 53.43 mL
1 mM 2.67 mL 13.36 mL 26.72 mL
5 mM 0.53 mL 2.67 mL 5.34 mL

*The above data is based on the productmolecular weight 374.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11439
Actions Inhibitor
M. Wt 374.3
Formula C18H13F3N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 778270-11-4
Synonyms GNF2,GNF-2
SMILES C1=CC(=CC(=C1)C(=O)N)C2=CC(=NC=N2)NC3=CC=C(C=C3)OC(F)(F)F

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