GNF-8625 monopyridin-N-piperazine hydrochloride

Catalog No.: A34976
Trk Receptor Inhibitor
GNF-8625 monopyridin-N-piperazine hydrochloride is a potent inhibitor of the Tropomyosin receptor kinase (Trk) family. This compound effectively disrupts the signaling pathways associated with Trk receptors, which are implicated in neurotrophic signaling and oncogenesis. GNF-8625 is utilized in research applications focused on neurobiology, cancer pharmacology, and targeted therapies to elucidate the role of Trk signaling in tumor growth and nerve regeneration.
Grouped product items
Size Price Stock Qty
1mg
$70.00
In stock
5mg
$205.00
In stock
10mg
$335.00
In stock
25mg
$715.00
In stock
50mg
$1,105.00
In stock
100mg
$1,560.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGNF-8625 monopyridin-N-piperazine hydrochloride is a potent inhibitor of the Tropomyosin receptor kinase (Trk) family. This compound effectively disrupts the signaling pathways associated with Trk receptors, which are implicated in neurotrophic signaling and oncogenesis. GNF-8625 is utilized in research applications focused on neurobiology, cancer pharmacology, and targeted therapies to elucidate the role of Trk signaling in tumor growth and nerve regeneration.
Product Information
Catalog NumA34976
FormulaC25H27ClFN7
Molecular Weight479.98
CAS Number2412055-62-8
SMILESFC1=CC([C@@H]2N(C3=NN4C(C=C3)=NC=C4C5=NC(N6CCNCC6)=CC=C5)CCC2)=CC=C1.[H]Cl
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