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GNQWFI

Catalog No.: A34733
VEGFR1 Antagonist
GNQWFI is a VEGFR1-specific antagonist that effectively disrupts the interaction between VEGFR1 and its ligands, including VEGFA, VEGFB, and placental growth factor (PlGF). This peptide inhibits VEGF-mediated endothelial cell migration and tube formation, making it a valuable tool for studying vasculature-related processes. GNQWFI has potential applications in cancer research, asthma, and various ocular diseases.
GNQWFI 853995-60-5 VEGFR1 Antagonist
Grouped product items
Size Price Stock Qty
5mg
$40.00
In stock
10mg
$65.00
In stock
25mg
$130.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGNQWFI is a VEGFR1-specific antagonist that effectively disrupts the interaction between VEGFR1 and its ligands, including VEGFA, VEGFB, and placental growth factor (PlGF). This peptide inhibits VEGF-mediated endothelial cell migration and tube formation, making it a valuable tool for studying vasculature-related processes. GNQWFI has potential applications in cancer research, asthma, and various ocular diseases.
Product Information
Catalog NumA34733
FormulaC37H49N9O9
Molecular Weight763.84
CAS Number853995-60-5
SequenceGly-Asn-Gln-Trp-Phe-Ile
Sequence shorteningGNQWFI
SMILESC([C@@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H]([C@H](CC)C)C(O)=O)=O)=O)NC([C@@H](NC([C@@H](NC(CN)=O)CC(N)=O)=O)CCC(N)=O)=O)C=2C=3C(NC2)=CC=CC3
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Protein Tyrosine Kinases > VEGFR
Angiogenesis > VEGFR