GSK3145095
Catalog No.: A19427
RIP1 kinase inhibitor
GSK3145095 is a RIP1 kinase inhibitor with an IC50 of 6.3 nM .
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Adooq Products cited in reputable paper
Biological Activity
| Description | GSK3145095 is a RIP1 kinase inhibitor with an IC50 of 6.3 nM . | |||||
|---|---|---|---|---|---|---|
| Cell Research |
|
Product Information
| Catalog Num | A19427 |
|---|---|
| Formula | C20H17F2N5O2 |
| Molecular Weight | 397.38 |
| CAS Number | 1622849-43-7 |
| SMILES | FC1=CC(F)=CC2=C1NC([C@@H](NC(C3=NNC(CC4=CC=CC=C4)=N3)=O)CC2)=O |
| Synonyms | GSK-3145095; GSK 3145095 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro | DMSO | 74 mg/mL (186.22 mM) | |
| Water | Insoluble | ||
| Ethanol | 6 mg/mL (15.09 mM) | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.16 mL | 125.82 mL | 251.65 mL |
| 0.5 mM | 5.03 mL | 25.16 mL | 50.33 mL |
| 1 mM | 2.52 mL | 12.58 mL | 25.16 mL |
| 5 mM | 0.5 mL | 2.52 mL | 5.03 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
