GSK3145095

Catalog No.: A19427

RIP1 kinase inhibitor

GSK3145095

GSK3145095 Chemical Structure

CAS NO. 1622849-43-7

GSK3145095 is a RIP1 kinase inhibitor with an IC50 of 6.3 nM .

Availability: In stock

Package Price Qty
1 mg

Regular Price: $110.00

Special Price $88.00

5 mg

Regular Price: $330.00

Special Price $264.00

10 mg

Regular Price: $560.00

Special Price $448.00

50 mg

Regular Price: $1,680.00

Special Price $1,344.00

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Biological Activity

GSK3145095 is a RIP1 kinase inhibitor with an IC50 of 6.3 nM .
In vitro DMSO 74 mg/mL (186.22 mM)
Water Insoluble
Ethanol 6 mg/mL (15.09 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.16 mL 125.82 mL 251.65 mL
0.5 mM 5.03 mL 25.16 mL 50.33 mL
1 mM 2.52 mL 12.58 mL 25.16 mL
5 mM 0.5 mL 2.52 mL 5.03 mL

*The above data is based on the productmolecular weight 397.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A19427
Actions Inhibitor
CAS No. 1622849-43-7
Formula C20H17F2N5O2
M. Wt 397.38
Purity >98%
Synonyms GSK-3145095; GSK 3145095
SMILES FC1=CC(F)=CC2=C1NC([[email protected]@H](NC(C3=NNC(CC4=CC=CC=C4)=N3)=O)CC2)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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