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Biological Activity
GZD824 is a novel orally bioavailable inhibitor against a broad spectrum of Bcr-Abl mutants including T315I.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.79 mL | 93.95 mL | 187.89 mL |
| 0.5 mM | 3.76 mL | 18.79 mL | 37.58 mL |
| 1 mM | 1.88 mL | 9.39 mL | 18.79 mL |
| 5 mM | 0.38 mL | 1.88 mL | 3.76 mL |
*The above data is based on the productmolecular weight 532.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16264 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1257628-77-5 |
| Formula | C29H27F3N6O |
| M. Wt | 532.22 |
| Purity | >98% |
| Synonyms | GZD 824, GZD-824 |
| SMILES | CC1=CC=C(C=C1C#CC2=CN=C3C(C=NN3)=C2)C(NC4=CC=C(C(C(F)(F)F)=C4)CN5CCN(CC5)C)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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