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H3B-6527

FGFR4 inhibitor

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Catalog No. A16252

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
H3B-6527 1mg A16252-1
€114.00
H3B-6527 5mg A16252-5
€304.00
H3B-6527 10mg A16252-10
€437.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

H3B-6527 is a highly selective FGFR4 inhibitor with potent antitumour activity in FGF19 amplified cell lines and mice.

H3B-6527

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Chemical Information

Catalog Num A16252
Actions Inhibitor
M. Wt 629.54
Formula C29H34Cl2N8O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1702259-66-2
Synonyms H3B6527, H3B 6527
SMILES C=CC(NC1=CC(N2CCN(CC)CC2)=CC=C1NC3=NC=NC(N(C(NC4=C(Cl)C(OC)=CC(OC)=C4Cl)=O)C)=C3)=O

Biological Activity

Description
H3B-6527 is a highly selective FGFR4 inhibitor with potent antitumour activity in FGF19 amplified cell lines and mice.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.88 mL 79.42 mL 158.85mL
0.5 mM 3.18 mL 15.88 mL 31.77 mL
1 mM 1.59 mL 7.94 mL 15.88 mL
5 mM 0.32 mL 1.59 mL 3.18 mL

*The above data is based on the productmolecular weight 629.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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