HA14-1

Catalog No.: A11448

Bcl-2 inhibitor

HA14-1

HA14-1 Chemical Structure

CAS NO. 65673-63-4

HA14-1 interacts with Bcl-2 and inhibits the antiapoptotic effect of Bcl-2.

Availability: In stock

Package Price Qty
10 mg
$40.00
25 mg
$70.00
50 mg
$110.00
100 mg
$200.00
10mM * 1mL in DMSO
$75.00
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Biological Activity

HA14-1 interacts with Bcl-2 and inhibits the antiapoptotic effect of Bcl-2.
Targets
Bcl-2
9 μM
In vitro (25°C) DMSO 80 mg/mL (195.48 mM)
Water Insoluble
Ethanol 80 mg/mL (195.48 mM)
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.44 mL 122.19 mL 244.38 mL
0.5 mM 4.89 mL 24.44 mL 48.88 mL
1 mM 2.44 mL 12.22 mL 24.44 mL
5 mM 0.49 mL 2.44 mL 4.89 mL

*The above data is based on the productmolecular weight 409.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11448
Actions Inhibitor
CAS No. 65673-63-4
Formula C17H17BrN2O5
M. Wt 409.2
Purity >98%
SMILES CCOC(=O)C1=C(OC2=C(C1C(C#N)C(=O)OCC)C=C(C=C2)Br)N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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