HG-12-6

Name: HG-12-6
Brand: Adooq Bioscience
SKU: A64951
Rating: 5 (288 reviews)

Catalog No.: A64951

IRAK4 Type II Inhibitor

HG-12-6 is a type II inhibitor of IRAK4, exhibiting preferential binding to unphosphorylated inactive IRAK4 with an IC50 of 165 nM. This compound effectively modulates IRAK4 activity, making it a valuable tool for studying its role in autoimmunity and inflammation. Researchers can utilize HG-12-6 to investigate pathways associated with immune responses and inflammatory disorders.

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HG-12-6 2222354-57-4 IRAK4 Type II Inhibitor

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Grouped product items
Size	Price	Stock
25mg	$2,285.00	In stock
50mg	$2,935.00	In stock
100mg	$3,920.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	HG-12-6 is a type II inhibitor of IRAK4, exhibiting preferential binding to unphosphorylated inactive IRAK4 with an IC50 of 165 nM. This compound effectively modulates IRAK4 activity, making it a valuable tool for studying its role in autoimmunity and inflammation. Researchers can utilize HG-12-6 to investigate pathways associated with immune responses and inflammatory disorders.

Product Information

Catalog Num	A64951
Formula	C29H27F3N6O2S
Molecular Weight	580.62
CAS Number	2222354-57-4
SMILES	O=C(NC1=CC=C(CN2CCNCC2)C(C(F)(F)F)=C1)C3=CC=CC(C4=CC=C5C(SC(NC(C6CC6)=O)=N5)=N4)=C3

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