HIF-1/2α-IN-2 is a selective inhibitor of hypoxia-inducible factors HIF-1 and HIF-2α, effectively reducing their levels in biological systems. This compound triggers an iron starvation response by specifically targeting Iron Sulfur Cluster Assembly 2 (ISCA2). HIF-1/2α-IN-2 is utilized in research focused on tumor biology, ischemia, and metabolic disorders, contributing to a deeper understanding of cellular responses to hypoxia and iron dynamics.
HIF-1/2α-IN-2 is a selective inhibitor of hypoxia-inducible factors HIF-1 and HIF-2α, effectively reducing their levels in biological systems. This compound triggers an iron starvation response by specifically targeting Iron Sulfur Cluster Assembly 2 (ISCA2). HIF-1/2α-IN-2 is utilized in research focused on tumor biology, ischemia, and metabolic disorders, contributing to a deeper understanding of cellular responses to hypoxia and iron dynamics.
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