HIF-2α-IN-11 is a specific inhibitor of Hypoxia-Inducible Factor 2 alpha (HIF-2α), exhibiting an IC50 of 59.2 nM. This compound effectively disrupts HIF-2α activity, which is crucial in various biological processes, including cellular responses to hypoxia and tumorigenesis. Research applications include studies on cancer metabolism, angiogenesis, and the role of HIF-2α in pathological conditions associated with oxygen deficiency.
HIF-2α-IN-11 is a specific inhibitor of Hypoxia-Inducible Factor 2 alpha (HIF-2α), exhibiting an IC50 of 59.2 nM. This compound effectively disrupts HIF-2α activity, which is crucial in various biological processes, including cellular responses to hypoxia and tumorigenesis. Research applications include studies on cancer metabolism, angiogenesis, and the role of HIF-2α in pathological conditions associated with oxygen deficiency.
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