HIF-2α-IN-16

Catalog No.: A75618
HIF-2α Inhibitor
HIF-2α-IN-16 is a selective inhibitor of hypoxia-inducible factor 2 alpha (HIF-2α), exhibiting an IC50 of 0.091 μM. This compound demonstrates significant biological activity by interfering with HIF-2α signaling pathways, which are implicated in various cancerous conditions and other hypoxic responses. HIF-2α-IN-16 is commonly utilized in research to investigate its effects on tumor growth, metabolism, and related therapeutic approaches.
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5mg
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHIF-2α-IN-16 is a selective inhibitor of hypoxia-inducible factor 2 alpha (HIF-2α), exhibiting an IC50 of 0.091 μM. This compound demonstrates significant biological activity by interfering with HIF-2α signaling pathways, which are implicated in various cancerous conditions and other hypoxic responses. HIF-2α-IN-16 is commonly utilized in research to investigate its effects on tumor growth, metabolism, and related therapeutic approaches.
Product Information
Catalog NumA75618
FormulaC15H13F7N2O2
Molecular Weight386.26
CAS Number3033981-97-1
SMILESO=C(C1=CC=C(F)C(C(F)F)=N1)N2[C@@]3(CCC(F)(C3)F)[C@@H](C(F)(C2)F)O
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