Homocarbonyltopsentin

Catalog No.: A18702

Homocarbonyltopsentin

Homocarbonyltopsentin Chemical Structure

CAS NO. 172286-77-0

Homocarbonyltopsentin (PK4C9) is a small-molecule TSL2-binding compound, binds to pentaloop conformations of TSL2 and promotes a shift to triloop conformations that display enhanced SMN2 exon 7 (E7) splicing with EC50 value of 16 μM.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Homocarbonyltopsentin (PK4C9) is a small-molecule TSL2-binding compound, binds to pentaloop conformations of TSL2 and promotes a shift to triloop conformations that display enhanced SMN2 exon 7 (E7) splicing with EC50 value of 16 μM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27 mL 135 mL 270.01 mL
0.5 mM 5.4 mL 27 mL 54 mL
1 mM 2.7 mL 13.5 mL 27 mL
5 mM 0.54 mL 2.7 mL 5.4 mL

*The above data is based on the productmolecular weight 370.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18702
M. Wt 370.36
Formula C21H14N4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 172286-77-0
SMILES O=C(C1=NC=C(C(C2=CNC3=C2C=CC=C3)=O)N1)C4=CNC5=C4C=CC(O)=C5

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy Homocarbonyltopsentin | Homocarbonyltopsentin Supplier | purchase | cost | manufacturer | order | distributor | buy 172286-77-0| 172286-77-0 Supplier | purchase 172286-77-0 | 172286-77-0 cost | 172286-77-0 manufacturer | order 172286-77-0 | 172286-77-0 distributor
Rewards