Homocarbonyltopsentin

Name: Homocarbonyltopsentin
Brand: Adooq Bioscience
SKU: A18702
Rating: 5 (288 reviews)

Catalog No.: A18702

Homocarbonyltopsentin (PK4C9) is a small-molecule TSL2-binding compound, binds to pentaloop conformations of TSL2 and promotes a shift to triloop conformations that display enhanced SMN2 exon 7 (E7) splicing with EC50 value of 16 μM.

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Grouped product items
Size	Price	Stock
1mg	$90.00	In stock
5mg	$225.00	In stock
10mg	$360.00	In stock
25mg	$760.00	In stock
50mg	$1,200.00	In stock
100mg	$1,935.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	Homocarbonyltopsentin (PK4C9) is a small-molecule TSL2-binding compound, binds to pentaloop conformations of TSL2 and promotes a shift to triloop conformations that display enhanced SMN2 exon 7 (E7) splicing with EC50 value of 16 μM.

Product Information

Catalog Num	A18702
Formula	C21H14N4O3
Molecular Weight	370.36
CAS Number	172286-77-0
SMILES	O=C(C1=NC=C(C(C2=CNC3=C2C=CC=C3)=O)N1)C4=CNC5=C4C=CC(O)=C5
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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