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Homocarbonyltopsentin

Catalog No.: A18702
Homocarbonyltopsentin (PK4C9) is a small-molecule TSL2-binding compound, binds to pentaloop conformations of TSL2 and promotes a shift to triloop conformations that display enhanced SMN2 exon 7 (E7) splicing with EC50 value of 16 μM.
Homocarbonyltopsentin
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Product Name Price Stock Qty
Homocarbonyltopsentin 1mg
$320.00
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Homocarbonyltopsentin 5mg
$960.00
In stock
Homocarbonyltopsentin 10mg
$1,600.00
In stock
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Biological Activity
Discription Homocarbonyltopsentin (PK4C9) is a small-molecule TSL2-binding compound, binds to pentaloop conformations of TSL2 and promotes a shift to triloop conformations that display enhanced SMN2 exon 7 (E7) splicing with EC50 value of 16 μM.
Product Information
Catalog Num A18702
Formula C21H14N4O3
Molecular Weight 370.36
CAS Number 172286-77-0
SMILES O=C(C1=NC=C(C(C2=CNC3=C2C=CC=C3)=O)N1)C4=CNC5=C4C=CC(O)=C5
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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