Idasanutlin (RG7388)

Catalog No.: A14211

MDM2/p53 Inhibitor

Idasanutlin (RG7388)

Idasanutlin (RG7388) Chemical Structure

CAS NO. 1229705-06-9

Idasanutlin is a potent and selective p53-MDM2 inhibitor.

Availability: In stock

Package Price Qty
5 mg
$65.00
10 mg
$110.00
25 mg
$225.00
10mM * 1mL in DMSO
$80.00
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Biological Activity

Idasanutlin is a potent and selective p53-MDM2 inhibitor.
Targets
Mdm2
In vitro (25°C) DMSO 88 mg/mL (142.74 mM)
Water Insoluble
Ethanol Warmed: 7 mg/mL (11.35 mM)
In vivo 5% DMSO+30% PEG 300+5% Tween 80+ddH2O 6.1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.22 mL 81.11 mL 162.21 mL
0.5 mM 3.24 mL 16.22 mL 32.44 mL
1 mM 1.62 mL 8.11 mL 16.22 mL
5 mM 0.32 mL 1.62 mL 3.24 mL

*The above data is based on the productmolecular weight 616.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14211
Actions Inhibitor
CAS No. 1229705-06-9
Formula C31H29Cl2F2N3O4
M. Wt 616.48
Purity >98%
Synonyms RG-7388
SMILES CC(C)(C)C[[email protected]]1[[email protected]]([[email protected]]([[email protected]@H](N1)C(=O)NC2=C(C=C(C=C2)C(=O)O)OC)C3=C(C(=CC=C3)Cl)F)(C#N)C4=C(C=C(C=C4)Cl)F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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