Idasanutlin (RG7388)
Catalog No.: A14211
MDM2/p53 Inhibitor
Idasanutlin is a potent and selective p53-MDM2 inhibitor.
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Biological Activity
| Description | Idasanutlin is a potent and selective p53-MDM2 inhibitor. | |||||
|---|---|---|---|---|---|---|
| Targets |
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| Cell Research |
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Product Information
| Catalog Num | A14211 |
|---|---|
| Formula | C31H29Cl2F2N3O4 |
| Molecular Weight | 616.48 |
| CAS Number | 1229705-06-9 |
| SMILES | CC(C)(C)C[C@H]1[C@]([C@H]([C@@H](N1)C(=O)NC2=C(C=C(C=C2)C(=O)O)OC)C3=C(C(=CC=C3)Cl)F)(C#N)C4=C(C=C(C=C4)Cl)F |
| Synonyms | RG-7388 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | 88 mg/mL (142.74 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 7 mg/mL (11.35 mM) | ||
| In vivo | 5% DMSO+30% PEG 300+5% Tween 80+ddH2O | 6.1 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.22 mL | 81.11 mL | 162.21 mL |
| 0.5 mM | 3.24 mL | 16.22 mL | 32.44 mL |
| 1 mM | 1.62 mL | 8.11 mL | 16.22 mL |
| 5 mM | 0.32 mL | 1.62 mL | 3.24 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
