Idasanutlin (RG7388)

Catalog No.: A14211
MDM2/p53 Inhibitor
Idasanutlin is a potent and selective p53-MDM2 inhibitor.
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Idasanutlin 5mg
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Idasanutlin 10mg
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Idasanutlin 25mg
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Idasanutlin 10mM * 1mL in DMSO
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Biological Activity
Discription Idasanutlin is a potent and selective p53-MDM2 inhibitor.
Target Value
Product Information
Catalog Num A14211
Formula C31H29Cl2F2N3O4
Molecular Weight 616.48
CAS Number 1229705-06-9
SMILES CC(C)(C)C[C@H]1[C@]([C@H]([C@@H](N1)C(=O)NC2=C(C=C(C=C2)C(=O)O)OC)C3=C(C(=CC=C3)Cl)F)(C#N)C4=C(C=C(C=C4)Cl)F
Synonyms RG-7388

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

In vitro (25°C) DMSO 88 mg/mL (142.74 mM)
Water Insoluble
Ethanol Warmed: 7 mg/mL (11.35 mM)
In vivo 5% DMSO+30% PEG 300+5% Tween 80+ddH2O 6.1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.22 mL 81.11 mL 162.21 mL
0.5 mM 3.24 mL 16.22 mL 32.44 mL
1 mM 1.62 mL 8.11 mL 16.22 mL
5 mM 0.32 mL 1.62 mL 3.24 mL
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