IDF-11774

Catalog No.: A16845

HIF-1 inhibitor

IDF-11774

IDF-11774 Chemical Structure

CAS NO. 1429054-28-3

Biological Activity
Description IDF-11774 is a hypoxia-inducible factor-1 (HIF-1) inhibitor. It reduces the HRE-luciferase activity of HIF-1α (IC50 = 3.65 μM) and blocks HIF-1α accumulation under hypoxia in HCT116 human colon cancer cells.

Availability: In stock

Package Price Qty
2 mg
$90.00
5 mg
$130.00
10 mg
$220.00
50 mg
$670.00
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Biological Activity

Biological Activity Description IDF-11774 is a hypoxia-inducible factor-1 (HIF-1) inhibitor. It reduces the HRE-luciferase activity of HIF-1α (IC50 = 3.65 μM) and blocks HIF-1α accumulation under hypoxia in HCT116 human colon cancer cells.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.14 mL 135.68 mL 271.36 mL
0.5 mM 5.43 mL 27.14 mL 54.27 mL
1 mM 2.71 mL 13.57 mL 27.14 mL
5 mM 0.54 mL 2.71 mL 5.43 mL

*The above data is based on the productmolecular weight 368.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16845
Actions Inhibitor
M. Wt 368.51
Formula C23H32N2O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1429054-28-3
Synonyms IDF11774, IDF 11774
SMILES O=C(N1CCN(C)CC1)COC2=CC=C(C34C[[email protected]]5C[[email protected]@](C4)([H])C[[email protected]](C5)C3)C=C2

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