IRAK1/4/pan-FLT3 Kinase-IN-2 is a dual inhibitor targeting IRAK1, IRAK4, and FLT3 with IC50 values of 10 nM, 0.7 nM, and <0.5 nM, respectively. This compound demonstrates significant biological activity by extending survival in acute myeloid leukemia model mice. It serves as a valuable tool for research in hematological malignancies and associated therapeutic pathways, facilitating studies on the modulation of kinase activity in cancer.
IRAK1/4/pan-FLT3 Kinase-IN-2 is a dual inhibitor targeting IRAK1, IRAK4, and FLT3 with IC50 values of 10 nM, 0.7 nM, and <0.5 nM, respectively. This compound demonstrates significant biological activity by extending survival in acute myeloid leukemia model mice. It serves as a valuable tool for research in hematological malignancies and associated therapeutic pathways, facilitating studies on the modulation of kinase activity in cancer.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
