IRAK4 ligand-13

Catalog No.: A64936
IRAK4 ligand
IRAK4 ligand-13 is a selective ligand targeting IRAK4, a key component in the interleukin-1 receptor and Toll-like receptor signaling pathways. This compound is designed for the development of proteolysis-targeting chimeras (PROTACs), facilitating targeted protein degradation. It is suitable for research applications aimed at modulating immune responses and studying signaling pathways associated with inflammation and cancer.
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5mg
10mg
50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionIRAK4 ligand-13 is a selective ligand targeting IRAK4, a key component in the interleukin-1 receptor and Toll-like receptor signaling pathways. This compound is designed for the development of proteolysis-targeting chimeras (PROTACs), facilitating targeted protein degradation. It is suitable for research applications aimed at modulating immune responses and studying signaling pathways associated with inflammation and cancer.
Product Information
Catalog NumA64936
FormulaC23H26N10
Molecular Weight442.52
CAS Number3023848-94-1
SMILESCC1(CC1)NC2=NC(NC3=CN(C4CCNCC4)N=C3)=NC5=CC=C(C6=CN=CN=C6)N=C52
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