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Biological Activity
ITK inhibitor 2 is a interleukin-2-inducible T-cell kinase (ITK) inhibitor extracted from patent WO2011065402A1, compound 4, with an IC50 of 2 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.96 mL | 114.79 mL | 229.59 mL |
| 0.5 mM | 4.59 mL | 22.96 mL | 45.92 mL |
| 1 mM | 2.3 mL | 11.48 mL | 22.96 mL |
| 5 mM | 0.46 mL | 2.3 mL | 4.59 mL |
*The above data is based on the productmolecular weight 435.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A19096 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1309784-09-5 |
| Formula | C25H33N5O2 |
| M. Wt | 435.56 |
| Purity | >98% |
| SMILES | CC1(CC2=C(C(C3=CC4=CC=C(N(C)C([[email protected]@H](N5CCOCC5)C)=O)C=C4N3)=NN2)CC1)C |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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