JH-VIII-157-02

Name: JH-VIII-157-02
Brand: Adooq Bioscience
SKU: A20205
Rating: 5 (288 reviews)

Catalog No.: A20205

ALK inhibitor

JH-VIII-157-02 is a structural analogue of alectinib, acts as an ALK inhibitor, and shows an IC50 of 2 nM for echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) G1202R in cells.

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JH-VIII-157-02 1639422-97-1 ALK inhibitor

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Grouped product items
Size	Price	Stock
1mg	$110.00	In stock
5mg	$245.00	In stock
10mg	$370.00	In stock
25mg	$580.00	In stock
50mg	$785.00	In stock
100mg	$1,085.00	In stock
*10mM 1mL in DMSO**	$250.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description

JH-VIII-157-02 is a structural analogue of alectinib, acts as an ALK inhibitor, and shows an IC50 of 2 nM for echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) G1202R in cells.

Cell Research

Cell Line	Type	Value	Description	References

Product Information

Catalog Num	A20205
Formula	C28H27N5O2
Molecular Weight	465.55
CAS Number	1639422-97-1
SMILES	O=C(N(C)C)CN1N=CC(C2=C(CC)C=C3C(C(C)(C)C(NC4=C5C=CC(C#N)=C4)=C5C3=O)=C2)=C1
Synonyms	JH-VIII-15702; JH-VIII-157 02; JHVIII-157-02; JHVIII-15702; JHVIII-157 02; JH815702; JH-815702; JH 815702
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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