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JI-101 is an orally active inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor beta (PDGFRβ), and the ephrin B4 receptor B4 (EphB4) with potential antiangiogenic and antineoplastic activities.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.44 mL | 107.22 mL | 214.44 mL |
| 0.5 mM | 4.29 mL | 21.44 mL | 42.89 mL |
| 1 mM | 2.14 mL | 10.72 mL | 21.44 mL |
| 5 mM | 0.43 mL | 2.14 mL | 4.29 mL |
*The above data is based on the productmolecular weight 466.3305. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13545 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 466.3305 |
| Formula | C22H20BrN5O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 900573-88-8 |
| Synonyms | JI 101, JI101 |
| SMILES | COC1=C(C=C(C=C1)Br)NC(=O)NC2=CC=CC3=C2C=CN3CC4=CC(=NC=C4)N |
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