JI-101

Catalog No.: A13545

VEGFR2/PDGFRβ/EphB4 inhibitor

JI-101 Chemical Structure

CAS NO. 900573-88-8

JI-101 is an orally active inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor beta (PDGFRβ), and the ephrin B4 receptor B4 (EphB4) with potential antiangiogenic and antineoplastic activities.

Availability: In stock

Package Price Qty
5 mg
$140.00
10 mg
$205.00
25 mg
$420.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

JI-101 is an orally active inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor beta (PDGFRβ), and the ephrin B4 receptor B4 (EphB4) with potential antiangiogenic and antineoplastic activities.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.44 mL 107.22 mL 214.44 mL
0.5 mM 4.29 mL 21.44 mL 42.89 mL
1 mM 2.14 mL 10.72 mL 21.44 mL
5 mM 0.43 mL 2.14 mL 4.29 mL

*The above data is based on the productmolecular weight 466.3305. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13545
Actions Inhibitor
M. Wt 466.3305
Formula C22H20BrN5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 900573-88-8
Synonyms JI 101, JI101
SMILES COC1=C(C=C(C=C1)Br)NC(=O)NC2=CC=CC3=C2C=CN3CC4=CC(=NC=C4)N

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