JNJ-10198409

Name: JNJ-10198409
Brand: Adooq Bioscience
SKU: A22554
Rating: 5 (288 reviews)

Catalog No.: A22554

PDGFRα/PDGFRβ inhbitor

JNJ 10198409 is a potent platelet-derived growth factor receptor (PDGFR) inhibitor (IC50 values are 4.2 and 45 nM for PDGFRβ and PDGFRα, respectively). Also inhibits c-Abl, Lck, c-Src and Fyn kinases (IC50 values are 22, 100, 185 and 378 nM respectively).

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JNJ-10198409 627518-40-5 PDGFRα/PDGFRβ inhbitor

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Grouped product items
Size	Price	Stock
1mg	$20.00	In stock
5mg	$55.00	In stock
10mg	$95.00	In stock
25mg	$215.00	In stock
50mg	$320.00	In stock
100mg	$460.00	In stock
200mg	$645.00	In stock
*10mM 1mL in DMSO**	$100.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	JNJ 10198409 is a potent platelet-derived growth factor receptor (PDGFR) inhibitor (IC50 values are 4.2 and 45 nM for PDGFRβ and PDGFRα, respectively). Also inhibits c-Abl, Lck, c-Src and Fyn kinases (IC50 values are 22, 100, 185 and 378 nM respectively).

Product Information

Catalog Num	A22554
Formula	C18H16FN3O2
Molecular Weight	325.3434
CAS Number	627518-40-5
SMILES	COC1=CC2=C(C=C1OC)CC3=C2NN=C3NC4=CC=CC(F)=C4
Synonyms	JNJ-10198409, JNJ 10198409, JNJ10198409, RWJ-540973, RWJ 540973, RWJ540973.
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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