JNJ-10198409

Catalog No.: A22554
PDGFRα/PDGFRβ inhbitor
JNJ 10198409 is a potent platelet-derived growth factor receptor (PDGFR) inhibitor (IC50 values are 4.2 and 45 nM for PDGFRβ and PDGFRα, respectively). Also inhibits c-Abl, Lck, c-Src and Fyn kinases (IC50 values are 22, 100, 185 and 378 nM respectively).
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Product Name Price Stock Qty
JNJ-10198409 5mg
$60.00
In stock
JNJ-10198409 10mg
$100.00
In stock
JNJ-10198409 50mg
$380.00
In stock
JNJ-10198409 100mg
$680.00
In stock
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Biological Activity
Discription JNJ 10198409 is a potent platelet-derived growth factor receptor (PDGFR) inhibitor (IC50 values are 4.2 and 45 nM for PDGFRβ and PDGFRα, respectively). Also inhibits c-Abl, Lck, c-Src and Fyn kinases (IC50 values are 22, 100, 185 and 378 nM respectively).
Product Information
Catalog Num A22554
Formula C18H16FN3O2
Molecular Weight 325.3434
CAS Number 627518-40-5
SMILES COC1=CC2=C(C=C1OC)CC3=C2NN=C3NC4=CC=CC(F)=C4
Synonyms JNJ-10198409, JNJ 10198409, JNJ10198409, RWJ-540973, RWJ 540973, RWJ540973.
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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