K145

Catalog No.: A16288

SphK2 inhibitor

K145

K145 Chemical Structure

CAS NO. 1309444-75-4

K145 is a selective SphK2 inhibitor with an IC50 of 4.30± 0.06 μM , while no inhibition of SphK1 at concentrations up to 10 uM.

Availability: In stock

Package Price Qty
5 mg
$60.00
10 mg
$100.00
50 mg
$320.00
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Biological Activity

K145 is a selective SphK2 inhibitor with an IC50 of 4.30± 0.06 μM , while no inhibition of SphK1 at concentrations up to 10 uM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.7 mL 143.49 mL 286.98 mL
0.5 mM 5.74 mL 28.7 mL 57.4 mL
1 mM 2.87 mL 14.35 mL 28.7 mL
5 mM 0.57 mL 2.87 mL 5.74 mL

*The above data is based on the productmolecular weight 348.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16288
Actions Inhibitor
CAS No. 1309444-75-4
Formula C18H24N2O3S
M. Wt 348.46
Solubility DMSO
Purity >98%
Synonyms SphK2 inhibitor, K 145, K-145
SMILES CCCCOC1=CC=C(C=C1)CCC=C2C(=O)N(C(=O)S2)CCN
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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