KC7F2

Catalog No.: A15359

HIF inhibitor

KC7F2

KC7F2 Chemical Structure

CAS NO. 927822-86-4

KC7F2 is an inhibitor of HIF-1α protein translation, but not transcription, that suppresses phosphorylation of two key regulators of protein synthesis, eukaryotic translation initiation factor 4E binding protein 1 (4EBP1) and p70 S6 kinase (S6K).

Availability: In stock

Package Price Qty
10 mg

Regular Price: $70.00

Special Price $63.00

50 mg

Regular Price: $250.00

Special Price $225.00

100 mg

Regular Price: $420.00

Special Price $378.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

KC7F2 is an inhibitor of HIF-1α protein translation, but not transcription, that suppresses phosphorylation of two key regulators of protein synthesis, eukaryotic translation initiation factor 4E binding protein 1 (4EBP1) and p70 S6 kinase (S6K).
Targets
HIF-1α
20 μM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.53 mL 87.66 mL 175.32 mL
0.5 mM 3.51 mL 17.53 mL 35.06 mL
1 mM 1.75 mL 8.77 mL 17.53 mL
5 mM 0.35 mL 1.75 mL 3.51 mL

*The above data is based on the productmolecular weight 570.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15359
Actions Inhibitor
M. Wt 570.38
Formula C16H16Cl4N2O4S4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 927822-86-4
Synonyms N/A
SMILES C1=CC(=C(C=C1Cl)S(=O)(=O)NCCSSCCNS(=O)(=O)C2=C(C=CC(=C2)Cl)Cl)Cl

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