KC7F2

Name: KC7F2
Brand: Adooq Bioscience
SKU: A15359
Rating: 100 (268 reviews)

Catalog No.: A15359

HIF inhibitor

KC7F2 Chemical Structure

CAS NO. 927822-86-4

KC7F2 is an inhibitor of HIF-1α protein translation, but not transcription, that suppresses phosphorylation of two key regulators of protein synthesis, eukaryotic translation initiation factor 4E binding protein 1 (4EBP1) and p70 S6 kinase (S6K).

Availability: In stock

Package	Price	Qty
10 mg	$55.00
50 mg	$190.00
100 mg	$280.00
Custom Size	Get quote

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Biological Activity

Targets

HIF-1α
20 μM

Solubility *

In vitro	DMSO	94 mg/mL (164.8 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.53 mL	87.66 mL	175.32 mL
0.5 mM	3.51 mL	17.53 mL	35.06 mL
1 mM	1.75 mL	8.77 mL	17.53 mL
5 mM	0.35 mL	1.75 mL	3.51 mL

*The above data is based on the productmolecular weight 570.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num	A15359
Actions	Inhibitor
CAS No.	927822-86-4
Formula	C16H16Cl4N2O4S4
M. Wt	570.38
Solubility	DMSO
Purity	>98%
SMILES	C1=CC(=C(C=C1Cl)S(=O)(=O)NCCSSCCNS(=O)(=O)C2=C(C=CC(=C2)Cl)Cl)Cl
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.