Total item
Cart Subtotal
$0.00 Biological Activity
KC7F2 is an inhibitor of HIF-1α protein translation, but not transcription, that suppresses phosphorylation of two key regulators of protein synthesis, eukaryotic translation initiation factor 4E binding protein 1 (4EBP1) and p70 S6 kinase (S6K).
Targets
| HIF-1α | ||||
| 20 μM |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.53 mL | 87.66 mL | 175.32 mL |
| 0.5 mM | 3.51 mL | 17.53 mL | 35.06 mL |
| 1 mM | 1.75 mL | 8.77 mL | 17.53 mL |
| 5 mM | 0.35 mL | 1.75 mL | 3.51 mL |
*The above data is based on the productmolecular weight 570.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Chemical Properties
| Catalog Num | A15359 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 570.38 |
| Formula | C16H16Cl4N2O4S4 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 927822-86-4 |
| Synonyms | N/A |
| SMILES | C1=CC(=C(C=C1Cl)S(=O)(=O)NCCSSCCNS(=O)(=O)C2=C(C=CC(=C2)Cl)Cl)Cl |
Product Tags
Product Questions
Product Questions
No Questions
You may also be interested in the following product(s)
2-Methoxyestradiol
2-Methoxyestradiol is an apoptotic, antiproliferative and antiangiogenic agent. Induces p53-induced apoptosis via two pathways: activation o…
ML 228
ML-228 is an activator of the HIF signaling pathway, as demonstrated by HIF response element (HRE) reporter assay, HIF-1α nuclear transloca…
BAY 87-2243
BAY 87-2243, a highly potent and selective inhibitor of hypoxia-induced gene activation has antitumor activities by inhibition of mitochondr…
FM19G11
FM19G11 is an inhibitor of Hypoxia Inducible Factors α (HIFα), which are transcription factors that respond to changes in available oxygen…
FG-4592 (Roxadustat)
FG-4592 is a novel hypoxia inducible factor prolyl hydroxylase inhibitor, in CKD anemia.
Chetomin
Chetomin is reported to be an antibiotic metabolite of Chaetomium spp. which contains bacteriostatic effects on Gram-positive bacteria.
HIF-C2
HIF-C2 is a potent and selective allosteric inhibitor of hypoxia inducible factor-2 (HIF-2)
IOX 2
IOX2 is a potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) with IC50 of 21 nM in a cell-free assay, >100-fold selectivity over JMJD2A…
Keywords:buy KC7F2 | KC7F2 Supplier | purchase KC7F2 | KC7F2 cost | KC7F2 manufacturer | order KC7F2 | KC7F2 distributor | buy 927822-86-4| 927822-86-4 Supplier | purchase 927822-86-4 | 927822-86-4 cost | 927822-86-4 manufacturer | order 927822-86-4 | 927822-86-4 distributor
Adooq Quality Guarantee
We promise all products perform as described.