KRCA-0008

Catalog No.: A15511

ACK1/ALK inhibitor

KRCA-0008 Chemical Structure

CAS NO. 1472795-20-2

KRCA-0008 is a potent and selective ALK/Ack1 inhibitor with IC50 of 12 nM/4 nM for ALK and Ack1 respectively; displays drug-like properties without hERG liability.

Availability: In stock

Package Price Qty
10 mg
$110.00
25 mg
$200.00
50 mg
$390.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

KRCA-0008 is a potent and selective ALK/Ack1 inhibitor with IC50 of 12 nM/4 nM for ALK and Ack1 respectively; displays drug-like properties without hERG liability.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.42 mL 82.09 mL 164.17 mL
0.5 mM 3.28 mL 16.42 mL 32.83 mL
1 mM 1.64 mL 8.21 mL 16.42 mL
5 mM 0.33 mL 1.64 mL 3.28 mL

*The above data is based on the productmolecular weight 609.12. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15511
Actions Inhibitor
M. Wt 609.12
Formula C30H37ClN8O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1472795-20-2
Synonyms KRCA 0008, KRCA0008
SMILES CC(=O)N1CCN(CC1)C2=CC(=C(C=C2)NC3=NC(=NC=C3Cl)NC4=C(C=C(C=C4)N5CCN(CC5)C(=O)C)OC)OC

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