KRN 633

Catalog No.: A10504
VEGFR Inhibitor
KRN 633 is a cell-permeable, reversible, ATP-competitive VEGFR kinase inhibitor that inhibits PDGFR-α and c-Kit at higher concentrations only (IC50 = 0.97 μM and 4.33 μM, respectively) and inactive towards 17 other kinases (IC50 ??? 10 μM).
Grouped product items
Product Name Price Stock Qty
KRN 633 5mg
$80.00
In stock
KRN 633 10mg
$140.00
In stock
KRN 633 50mg
$340.00
In stock
KRN 633 100mg
$540.00
In stock
KRN 633 10mM * 1mL in DMSO
$90.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Biological Activity
Discription KRN 633 is a cell-permeable, reversible, ATP-competitive VEGFR kinase inhibitor that inhibits PDGFR-α and c-Kit at higher concentrations only (IC50 = 0.97 μM and 4.33 μM, respectively) and inactive towards 17 other kinases (IC50 ??? 10 μM).
Targets
Target Value
Product Information
Catalog Num A10504
Formula C20H21ClN4O4
Molecular Weight 416.9
CAS Number 286370-15-8
SMILES CCCNC(=O)NC1=C(C=C(C=C1)OC2=NC=NC3=CC(=C(C=C32)OC)OC)Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 8 mg/mL (19.18 mM)
Water Insoluble
Ethanol Insoluble
In vivo 0.5% methylcellulose+0.2% Tween 80 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.99 mL 119.93 mL 239.87 mL
0.5 mM 4.8 mL 23.99 mL 47.97 mL
1 mM 2.4 mL 11.99 mL 23.99 mL
5 mM 0.48 mL 2.4 mL 4.8 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
Keywords: buy KRN 633 | KRN 633 Supplier | purchase KRN 633 | KRN 633 cost | KRN 633 manufacturer | order KRN 633 | KRN 633 distributor | buy 286370-15-8 | 286370-15-8 Supplier | purchase 286370-15-8 | 286370-15-8 cost | 286370-15-8 manufacturer | order 286370-15-8 | 286370-15-8 distributor