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KTX-582 intermediate-2

Catalog No.: A33134
Intermediate
KTX-582 intermediate-2 is a crucial intermediate in the synthesis of KTX-582, which functions as an IRAK4 degrader and apoptosis inducer. This compound exhibits potent biological activity with DC50 values of 4 nM for IRAK4 and 5 nM for Ikaros. KTX-582 intermediate-2 is suitable for applications in antibody-drug conjugate (ADC) development and facilitates research into targeted therapies involving IRAK4 inhibition.
KTX-582 intermediate-2 2434850-07-2 Intermediate
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Size Price Stock Qty
5mg
$245.00
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10mg
$380.00
In stock
25mg
$800.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionKTX-582 intermediate-2 is a crucial intermediate in the synthesis of KTX-582, which functions as an IRAK4 degrader and apoptosis inducer. This compound exhibits potent biological activity with DC50 values of 4 nM for IRAK4 and 5 nM for Ikaros. KTX-582 intermediate-2 is suitable for applications in antibody-drug conjugate (ADC) development and facilitates research into targeted therapies involving IRAK4 inhibition.
Product Information
Catalog NumA33134
FormulaC21H27BrN4O5
Molecular Weight495.37
CAS Number2434850-07-2
SMILESO=C(N1C2C(NC(CC2)=O)=O)C3=CC=CC(N[C@H]4C[C@@H](C4)OCCCNC)=C3C1=O.Br
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Protein Tyrosine Kinases > IRAK