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KTX-582 intermediate-3

Catalog No.: A33029
Intermediate
KTX-582 intermediate-3 is a crucial intermediate in the synthesis of KTX-582, which functions as an IRAK4 degrader and apoptosis inducer. This compound exhibits potent biological activity, with DC50 values of 4 nM for IRAK4 and 5 nM for Ikaros. KTX-582 intermediate-3 is valuable for applications in antibody-drug conjugate (ADC) preparation and other research endeavors aimed at studying IRAK4-related pathways and apoptosis mechanisms.
KTX-582 intermediate-3 2573304-30-8 Intermediate
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionKTX-582 intermediate-3 is a crucial intermediate in the synthesis of KTX-582, which functions as an IRAK4 degrader and apoptosis inducer. This compound exhibits potent biological activity, with DC50 values of 4 nM for IRAK4 and 5 nM for Ikaros. KTX-582 intermediate-3 is valuable for applications in antibody-drug conjugate (ADC) preparation and other research endeavors aimed at studying IRAK4-related pathways and apoptosis mechanisms.
Product Information
Catalog NumA33029
FormulaC26H29F3N4O4
Molecular Weight518.53
CAS Number2573304-30-8
SMILESCC(O)(C1=C(NC(C2=CC=CC(C(F)(F)F)=N2)=O)C=C3C=NN([C@@H]4CC[C@H](CC4)C(OCC)=O)C3=C1)C
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Protein Tyrosine Kinases > IRAK